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According to Nakatsu et al., SGLT2 inhibitors, like luseogliflozin, suppress the development of atherosclerosis in diabetic mouse models and quickly restore inflammation-related gene expression in the aorta

Amjad Askary, Lindsey Mork, Sandeep Paul, Xinjun He, Audrey K Izuhara, Suhasni Gopalakrishnan, Justin K Ichida, Andrew P McMahon, Sonja Dabizljevic, Rodney Dale, Francesca V Mariani, J Gage Crump, "Iroquois proteins promote skeletal joint formation by maintaining chondrocytes in an immature state", Developmental cell, 35 (3): 358-365 (2015) [link]

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Regular L-Carnitine use has been linked to improved brain function and protection against age-related cognitive decline