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Retatrutide uses a different dose range (starting at 1 mg and going up to 12 mg in trials), different titration timing, and different concentrations when compounded

Yu X, Tsibane T, McGraw PA, House FS, Keefer CJ, Hicar MD, et al

doi: 10.2337/DB21-0193 13 RegnellSELernmark

Baruscotti M, Bucchi A, Milanesi R, Paina M, Barbuti A, Gnecchi-Ruscone T, Bianco E, Vitali-Serdoz L, Cappato R, DiFrancesco D (2017) A gain-of-function mutation in the cardiac pacemaker HCN4 channel increasing cAMP sensitivity is associated with familial Inappropriate Sinus Tachycardia