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74 Notably, the upregulation of ZEB1 inhibited expression of the gemcitabine transporter via ITGA3/ITGB1/31 signaling and c- JNK pathway, which leads to chemoresistance both in vitro and in vivo

This haplotype also increased basal type I IFN signatures in mice with no differences in Ifih1 gene expression and enhanced resistance and survival against encephalomyocarditis virus (113, 114)

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