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Per the American Diabetes Association (ADA) Standards of Care in Diabetes2026, diagnosis is confirmed by one of four criteria: fasting plasma glucose 126 mg/dL, 2-hour plasma glucose 200 mg/dL during a 75-g OGTT, A1C 6.5% (using an FDA-approved CLIA-certified method), or a random plasma glucose 200 mg/dL in a patient with classic hyperglycemia symptoms

Different patient populations, different trial designs, different enrollment criteria, and different measurement protocols all introduce noise that makes precise numerical comparisons between CagriSema and tirzepatide unreliable

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1 Though uncommon, liposarcoma may also metastasize