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2.2 Stress-responsive and dedifferentiated -cell states The characterization of -cell subpopulations has been advanced by single-nucleus RNA sequencing (snRNA-seq)

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When comparing patients who initiated treatment with exenatide (n=14,076, median follow-up: 969 days), to those starting dulaglutide (n=54,787, median follow-up: 948 days) or liraglutide (n=25,562, median follow-up: 1,007 days), no differences were found in the hazard of composite treatment for diabetic macular edema (DME) and/or proliferative DR: exenatide vs

Side Effects: Long-term use can sometimes cause side effects that outweigh the benefits, such as gastrointestinal discomfort from orlistat or nausea from semaglutide