Importantly, semaglutide is not measured in insulin units - there are no "units per mL" for semaglutide
Second, this analysis focused exclusively on a subset of GLP-1 RA therapies (specifically semaglutide and tirzepatide) and did not account for other common PCOS treatments, such as metformin, combined oral contraceptives, or anti-androgen therapies
Tolerability will be another factor of the GLP-1s as gastrointestinal (GI) adverse effects, risk for stomach paralysis, and pancreatitis are additional deterrents in continuation or initiation of treatment
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This is the expected range for the initial titration phase