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124 The activation of p38MAPK associated with the degree of lung function impairment and alveolar wall inflammation

14 This mixed phenotype of these mice may be at least in part explained by their impaired osteoclas-togenesis, because cocultures of osteoblasts from IGF-I null mice and osteoclast precursors from wild-type mice, as well as osteoblasts from wild-type mice and osteoclast precursors from IGF-I null mice showed reduced numbers of osteoclasts

Designed solely for parenteral use (drug administration by intravenous, intramuscular, or subcutaneous injection) following the addition of drugs