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Available at: Last accessed February 2026

Stability studies from US Patent 9850282B2 demonstrate that at pH 7.357.40, the arginine salt form maintains exceptional integrity across temperature challenges

Its particularly valuable for athletes, active individuals, and those recovering from musculoskeletal injuries

Gene expression on BDNF and SK-3 was quantified using real-time PCR, revealing that VPA reduced the expression BDNF, which plays a crucial role in synaptic plasticity and neuronal survival, and increased GSK-3, which is involved in neurodevelopment and neuroinflammation whereas crocin dose-dependently normalized both markers (Hosseini et al., 2025)