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Clin Exp Health Sci 13(4):753759 Ding D, Liu H, Qi W, Jiang H, Li Y, Wu X, Sun H, Gross K, Salvi R (2016) Ototoxic effects and mechanisms of loop diuretics

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According to NICE guidance (NG28), metformin remains the first-line pharmacological treatment for many people with type 2 diabetes in the UK, though SGLT2 inhibitors may be considered first-line in those with established cardiovascular disease, chronic kidney disease, or at high cardiovascular risk

Regular aerobic exercise is one of the most consistently studied interventions shown to increase BDNF expression and promote neuroplasticity