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In other words, the medications dosage is gradually increased over time to reach its optimal therapeutic level while also minimizing adverse side effects

Prime the pen or check the device as directed by the trial IFU before each use

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So patients who advance too quickly to a higher dose typically have more severe side effects and may not be able to tolerate the medication. There is no secret extra dose The idea of a golden dose may be tempting for patients, but safety must come first

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