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The discrepancy is too large to be dismissed as a chance finding, suggest the researchers, but could be the result of publication biassome studies might have been prioritized for publication because of the positive nature of their results whereas the unpublished datasets used in this study would not have been affected by any failure to publish null results

Conversely, pretreatment with NAC only significantly prevented the decrease in mitochondrial membrane potential of 0.25 mM PQ-challenged cells, having no apparent effect on untreated control or 1.0 mM PQ-challenged cells

GLP-1 receptor agonists Including semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) are peptide-based drugs that have completed full FDA review and carry approved indications for type 2 diabetes and obesity

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