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16,18,23 Similar to chronic alcohol use, malnutrition causes depletion of glutathione stores

Dogs receiving high-calorie intake (120% MER) exhibited a dose-dependent reduction in feed consumption and significant body weight decrease at doses of 236 mg and 492 mg of L-carnitine, independent of exercise, and this was mostly found in females

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Baseline testing should include serum IGF-1, fasting glucose, fasting insulin, HbA1c, comprehensive metabolic panel (to assess liver and kidney function), and lipid panel

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