Diagnosis typically involves blood tests including full blood count (showing macrocytosis), anti-intrinsic factor antibodies (which are specific for pernicious anaemia), and sometimes anti-parietal cell antibodies
Researchers also observed shifts in glucose uptake and sirtuin activity (the SIRT1 longevity protein family) when NNMT was blocked
By silencing NNMT, it enables a natural uptick in NAD levels, leading to enhanced mitochondrial function, lean mass preservation, and fat metabolism without overstimulation
Small batches, Miron violet glass packaging (which filters damaging light wavelengths), spray applicator to minimise air exposure and refrigerated storage
Yes, B12 injections are generally considered very safe, even without a diagnosed deficiency