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Regulation of CPTI by histone deacetylation Histone deacetylase 1 (HDAC1) has a crucial role in transcriptional repression of gene expression

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In a model of brain injury induced in male rats using a fluid percussion device, researchers noted a significant increase in caspase-3-positive neurons and Neu-N plus TUNEL-positive neurons around the lesion site 72 h post-injury (Tang et al., 2016)