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All we're proposing to clinicians is Hey, think about the patients who are at risk and have a strategy to monitor and mitigate that risk." In a secondary analysis, the scientists found that weight loss alone did not explain the increased risk, suggesting other mechanisms of action may be at play

Resulting adducts were analyzed using bottom-up proteomics, with or without LC fractionation prior to LC-MS/MS analysis on a quadrupole-time-of-flight instrument with data-dependent acquisition (DDA)