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For urgent concerns that are not immediately life-threatening, patients can contact NHS 111 for advice

- May improve libido and sexual health

These structural modifications result in approximately 98% albumin binding in physiological buffers and an extended plasma half-life compared to unmodified GLP-1 analogs in preclinical pharmacokinetic studies

Native GLP-1 has an extremely short half-life due to rapid degradation by dipeptidyl peptidase-4 (DPP-4), and GLP-1 receptor agonist analogues are engineered with structural modifications to confer resistance to enzymatic cleavage and extend circulating activity in experimental systems

They are also known to help with weight loss and have cardiovascular benefits