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PPARs as master regulators of carnitine homeostasis Genes regulated by peroxisome proliferator-activated receptor (PPAR) are involved in many biological processes such as fatty acid catabolism, ketogenesis and gluconeogenesis, and also play a key role in the regulation of carnitine homeostasis [189]

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Nevertheless, analysis of the mass isotopomer contribution of U- 13 C glucose to -GC and GSH showed that the levels of M + 2-labeled [ 13 C] --GC and M + 2- and M + 4-labeled [ 13 C]-GSH were reduced in shACTL6A-expressing cells (Fig