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The top six most common gastrointestinal reports were nausea (8,988, 42.23%), diarrhea (4,666, 21.93%), vomiting (4,660, 21.90%), upper abdominal pain (2,082, 9.78%), constipation (1,790, 8.41%), and pancreatitis (1,752, 8.23%)

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Seven of 8 patients died within 1 year

animal studies suggest similar effects on drug-seeking and relapse

They help signal fat cells to release stored energy instead of holding on tight