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The development of effective nutritional management strategies for DED is crucial due to its association with various factors such as inflammation, oxidative stress, deficiencies in polyunsaturated fatty acids (PUFAs), imbalanced PUFA ratios, and vitamin insufficiencies

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However, clinical studies, in humans, aimed at investigating the sedative, analgesic, anti-depressive, antimicrobial, and antiviral effects are still lacking even though there is available animal and cell culture data for some of these uses

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Yu D, Jayasi J, Womac A, Kearns A, Bae C