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These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance
Making the most of probiotics
The good news is that many users experience minimal or no nausea, and for those who do, there are numerous effective strategies to manage this common side effect
Retatrutide showed a 7.2% weight loss at the lowest dose over 24 weeks
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