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Quick Answer: GLP-1 medications typically make you feel full earlier and reduce hunger by slowing stomach emptying and affecting brain appetite centers, though initial side effects like nausea and bloating are common

Genetic Predispositions and Individual Response Variation Genetic variation in GLP-1 receptor, GIP receptor, and metabolic pathways contributes to differences in medication efficacy and side effect tolerance

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Some healthcare providers prescribe split dosing, dividing the weekly amount into two doses given three to four days apart

Authors: Rhea Manohar, MPH