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doi: 10.1136/annrheumdis-2012-201526 294 KarouzakisERazaKKollingCBuckleyCDGaySFilerAet al

70 The antioxidant properties of UA and its ability to inhibit oxidative stress may attenuate inflammatory damage to the nervous system and contribute to the maintenance of neuron number and function by inhibiting programmed apoptosis of neuronal cells, which protects against excessive neuronal cell damage

Additionally, vitamin B12 plays a vital role in homocysteine metabolism

The microbiome maintains intestinal barrier integrity, so toxins do not leak back into circulation

Another research on Swiss-derived SHR mice concluded that this tetrapeptide slows down the age-related declining estrous function and can lessen the occurrence of chromosomal abnormalities in bone marrow [2].Similarly, one in vitro experiment found that epitalon can slow down the aging process of oocytes