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High dose ( 0.5 mg/kg/d) or long-term use may lead to hypoglycemia, especially in patients with diabetes or insulin resistance

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Elevated circulating inflammatory markers, including C-reactive protein and leukocyte counts, have been consistently reported in PCOS populations, even after adjustment for adiposity [5, 6], suggesting that inflammatory processes may contribute to disease expression rather than merely reflect obesity-related confounding

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When using the semaglutide pen for type 2 diabetes, it is vital to be aware of hypoglycemias potential risks and symptoms