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Some patients may tolerate one medication better than the other based on their unique physiology or previous experiences with similar treatments

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A separate 2025 narrative review by McGuire and colleagues asked a blunter question in its title: "Regeneration or Risk?" [2] Their conclusion: the preclinical evidence is consistently positive, but the absence of human data makes it impossible to generate evidence-based practice guidelines

[5] This dual role serving as a coenzyme for carboxylases and modulating gene activity underlies biotins importance in cellular function