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In this study, CYP exposure induces a marked increase in MDA, a characteristic marker of lipid peroxidation that indicates the excessive formation of free radicals.[] In this experiment, the treatment with CYP decreased CAT activity

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With regard to the nine human CRF 1 variants, CRF 1ai , described, CRF 1a being the main wild type functional receptor while the other isoforms may modulate CRF signaling (Zmijewski and Slominski, 2010