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Subsequent work established that the same sequence exists in human plasma, saliva, and urine at concentrations that decline with age, and that the sequence is found as a subfragment of the alpha-2 chain of type I collagen, which means GHK is released into the tissue environment when collagen breaks down

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Upper limb spasticity : Muscle stiffness in the arms, elbows, or hands, often after a stroke or in patients with conditions like cerebral palsy or multiple sclerosis

Finally, two scenarios giving rise to a system effectively free from downregulation could further illuminate the findings of this work