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Low B12 causes weakness, fatigue, and depression, but also other symptoms, including numbness or tingling in the hands, feet, and legs

participants in this study were mostly premenopausal women (56)

Compare with those in BLM group, the top genes exhibiting significantly decreased expression were mostly involved in ECMreceptor interaction, cytokinecytokine receptor interaction, phagosome, chemokine signalling pathway, focal adhesion and PI3KAkt signalling pathway

Neurotransmitter systems and mental wellness Animal studies have looked at how this compound may interact with serotonin and dopamine systems, with a review noting region-specific changes in serotonin synthesis in the brain following peripheral administration