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Potential therapeutic applications The therapeutic potential of glutathione in treating cold sores and canker sores can be harnessed through various approaches: Topical formulations: Developing creams or gels containing glutathione for direct application to cold sores and canker sores could provide localized antioxidative and anti-inflammatory effects

Squeezing it too hard can cause it to regurgitate more pathogen-carrying saliva

Schwedhelm E, Tan-Andresen J, Maas R, Riederer U, Schulze F, et al

Most studies reviewed are short-term (typically 6 to 12 weeks) and do not provide information on the sustainability of the clinical benefits or potential adverse effects of prolonged use

Pain, warmth, or visible streaking away from the site (possible infection)