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doi: 10.1038/nature10213 78

Akkermansia deficiency and mucin depletion are implicated in intestinal barrier dysfunction as earlier event in the development of inflammation in interleukin-10-deficient mice

Nakamura Y, Watanabe J, Akazawa N, Hirata K, Kataoka K, Yokota M, et al

The NF-B signaling pathway is another key pathway in which zinc plays an important role

In both conditions, one would hypothesized that the glucose-dependency of GLP-1 is also lost given the lack of functional K ATP channels in the first, and the concomitant hyperglycemia in the second