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Coelenterazine H (5 M) was then added to the plates and luminescence signals measured 1 h thereafter using an EnVision multilabel plate reader (PerkinElmer) at 18 s intervals before and after ligand addition (25 C)

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Economic analyses suggest GLP-1 medications cost far more at retail than their estimated manufacturing prices, reflecting markups tied to patents, branding, and distribution

Since the newest drugs have proven so effective both at helping people lose weight and preventing other health problems doctors and policymakers want to expand access to GLP-1 medications

Researchers can consult registered protocols on ClinicalTrials.gov and review background pharmacology at the NIH National Library of Medicine