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What patients really need is evidence-based care that allows clinicians to adjust dosing over time so were using the right dose for the right patient at the right time. GLP-1 medications can be a game-changer, but they work best when used as part of a broader strategy that includes nutrition, physical activity and long-term support

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In conclusion, these data indicates GLP-1 but not metformin protects MG-induced beta cell apoptosis through improving mitochondrial function, and alleviating the prolonged AMPK activation

Microvascular recruitment is an early insulin effect that regulates skeletal muscle glucose uptake in vivo