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The review draws from original studies employing immortalized prostate cancer cells, as well as more complex experimental models, including animals and humans, that more accurately reflect the complexity of the in vivo tumor microenvironment

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In vitro and vivo study of tranilast protects from acute respiratory distress syndrome and early pulmonary fibrosis induced by smoke inhalation

Similarly, suppression of the cICD results in a 50% reduction in GSIS in INS-1 832/13 cells and in isolated rat islets [62]