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The best ways to prevent flares are to stay exceptionally well-hydrated, avoid high-purine foods, and aim for steady rather than overnight weight loss

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In rat experiments, a decrease in phylloquinone (vitamin K 1 ) and menaquinone-4 (a form of vitamin K 2 ) concentrations in extra-hepatic tissues was found in animals administered excess -tocopherol via the diet or by subcutaneous injection

However, basal somatostatin secretion and responses to glucagon were low at 3.5 mmol/l glucose (reflecting only weak glucose-stimulated somatostatin secretion), and we therefore focused on investigating somatostatin at higher glucose concentrations

This is the sweet spot of expected results at six months