Retatrutide is an investigational triple receptor agonist that simultaneously activates GLP-1, GIP, and glucagon receptors, distinguishing it from approved agents such as semaglutide or tirzepatide
Injection site matters for comfort but not significantly for effectiveness
The limits of the study Among the study's limitations: It was conducted within the VA health system, which serves a population that is mostly older, white and male, although Al-Aly said the results were consistent in more than 35,000 women
Compounded semaglutide through Hims is unavailable in some states, so check availability before getting too invested in the program
"One of the things that need improvement to the overall patient journey is trying to get as much information to patients as possible earlier in their journey, because it really does influence the path downstream," Reitano said