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This research was registered with the UMIN Clinical Trials Registry (Study ID: UMIN000045362)

doi: 10.1210/jc.2010-2905 49 FallahiPFerrariSMRagusaFRuffilliIEliaGPaparoSRet al

In 21 men with moderate erectile dysfunction, supplementation with 120 mg Pycnogenol per day over a period of three months significantly decreased total cholesterol from 5.41 to 4.98 mmol/L and LDL-cholesterol from 3.44 to 2.78 mmol/L (11)