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And more importantly, how do they compare to their biologic versions

This is the molecule's original and best-established part in biology, worked out over decades of study of mitochondrial metabolism

So thank you, David

If oral B12 replacement has been trialled in a person with metformin-associated B12 deficiency, I would suggest that a repeat measurement of B12 levels after 812 weeks is a good time to reassess whether absorption is adequate or whether a switch to intramuscular replacement is required