Specifically, serum levels of AGEs have been inversely associated with optimal outcomes in AF patients undergoing pulmonary vein isolation [112], while lower 1,5-anhydro-d-glucitol levels have been linked with worse prognosis in patients with CV disease [113,114,115,116,117]
Such patients are called "marginally responsive" herein
International guidelines highlight the need for more personalized treatment 1 , but the concept has not yet been systematically examined in randomized trials specifically designed to evaluate treatment responses in patients with different characteristics
And its still important to study whether similar benefits are apparent with other GLP-1 medications, including newer drugs that are combining GLP-1s with other compounds
If the drugs are effective long term, people lead healthier lives, there will be less productivity loss, less private cost, higher quality of life if you can nip obesity in the bud for a significant amount of people, you could save people so much discomfort, but you could also save society money, he said
