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Moon AL, Haan N, Wilkinson LS, Thomas KL, Hall J

The primary designation to be aware of is the Retatrutide RUO (Research Use Only) label, indicating that the substance is intended strictly for laboratory use

Ozempic and Wegovy are expensive medications, often around $1,000+ per month if paid out of pocket, and they are not always covered by insurance when they are used for weight loss

For a frame of reference, tirzepatide achieved less than 20% weight loss at 36 weeks in their phase 2 trial

This dose titration happens with both compounded and FDA-approved versions - but the "Personalized+" naming emphasizes the customized nature of compounded pharmacy preparation