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doi: 10.1016/j.joca.2019.06.011 2 CaoS.WeiY.XiongA.YueY.YangJ.WangD.et al

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Some might notice changes in their appetite and blood glucose levels within a few weeks, while significant weight loss can take several months

Conclusions These findings suggest that microglial GLP-1R activation in the TNC may suppress the central sensitization of CM by regulating TNC microglial activation via the PI3K/Akt pathway