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For weight management specifically, options include semaglutide (Wegovy), liraglutide (Saxenda), or naltrexone/bupropion (Mysimba), though their efficacy is generally more modest than that of GLP-1-based therapies

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A Prime Therapeutics study also found that adherence to these drugs was poor, with 71% of individuals taking GLP-1 drugs discontinuing use after one year and 85% after two years

This makes it a valuable tool for those looking to manage their weight, balance blood sugar levels, or improve gut health

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