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Despite producing more weight loss, tirzepatide had lower rates of treatment discontinuation due to gastrointestinal adverse events (2.7% vs 5.6% for semaglutide)

Since these drugs slow gastric emptying, adding fatty foods that are already slow to digest can intensify feelings of nausea, bloating, and abdominal discomfort

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Roughly 45% of the 2,500 patients in the Phase 3 trial achieved 30% or more weight loss, Lilly said

Broadened Therapeutic Applications: Emerging evidence suggests that microdosing GLP-1 RAs might benefit conditions beyond diabetes and obesity, such as: Cognitive decline Arthritis Metabolic dysfunction Immune function Cardiovascular health Improved Cost-Effectiveness: Using less medication may lower treatment costs