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Concurrently, elevated p-tau levels induce reactive ROS overproduction and enhance GTPase activity of Drp1, directly driving pathological mitochondrial hyperfission and functional collapse in neurons (Pradeepkiran and Reddy, 2020)

Klein-Nulend et al., 2012)

Other types of cancer are acceptable if the cancer has been treated successfully and it has been more than 12 months since treatment was completed and there has been no cancer recurrence in this time