This information is for research reference only
On a GLP-1 the risk usually isn't eating too much it's not getting enough protein, fiber, and fluid into a smaller appetite.
Options include: Metoclopramide : May help with delayed gastric emptying but should only be used for short courses (maximum 5 days) due to risk of neurological side effects Prochlorperazine : Can be effective for nausea and vomiting Cyclizine : An alternative that works through a different mechanism Ondansetron : Sometimes used but may cause constipation Domperidone : Used cautiously due to risk of heart rhythm problems (QT prolongation), particularly in older adults, those with heart conditions, or those taking other medications affecting heart rhythm For people with diabetes, it's important to follow sick-day rules if experiencing vomiting
The decision is significant for the broader GLP-1 multidistrict litigation, where plaintiffs allege drug manufacturers failed to adequately warn consumers about risks including gastroparesis, bowel obstruction, ileus, and other injuries while aggressively marketing the medications for weight loss
doi: 10.1038/nrmicro.2016.94 36 FlickM