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Although this protective role of astrocytes on neuronal death by paraquat is quite promising, only few studies address this interaction and further research is needed in order to establish the precise effect of paraquat in astrocytes metabolism and neuroprotection
[DOI] [PMC free article] [PubMed] [Google Scholar] 126.Ip EJ, Barnett MJ, Tenerowicz MJ, Perry PJ
the differential response at dynamic PDU in mildmoderate and severe vasculogenic ED highlighted by the current study might rely on an insufficient intracavernous l-ARG delivery, upon oral administration of l-ARG at the tested doses, unable to counteract a severe vascular impairment, therefore suggesting the potential requirement of higher l-ARG supplementation regimens in these patients, although in some cases of severe vasculogenic ED an irreversible vascular damage cannot be ruled out
