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Manages cardiovascular health

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It is an acylated analog of human GLP-1, sharing 94% sequence homology with native GLP-1(7-37)

Furthermore, TGF- downregulates or inhibits the activities of SOD, catalase, and glutaredoxin (Grx)

Sitagliptin Liraglutide is a long-acting GLP-1RA that has been modified to non-covalently bind to serum albumin through addition of an acyl side chain, resulting in slower degradation (half-life 1115 h) and allowing for once-daily, subcutaneous dosing ( Pratley et al