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Small molecules that stabilize the Prx6selenium intermediate or enhance its interaction with SEPHS2 could augment GPX4 biosynthesis, whereas pharmacological inhibition of this pathway may sensitize cancer cells to ferroptosis-inducing therapies

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Reduction in Oxidative Stress Improvement in GSH Levels : The intervention group (DG) showed a significant increase in GSH levels, rising from a baseline median of ~ 440 M to ~ 1000 M after six months ( Cohen's d = 1