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3B) mRNA expression, regardless of the treatment conditions

The analyses were conducted on the above cohorts: (1) SGLT2i and (2) GLP-1 RA with each analysis propensity score matched (PSM) for age, sex, BMI, presence of heart failure (ICD-10-CM-I50), hypertension (ICD-10-CM-I10), ischaemic heart disease (IHD) (ICD-10-CM-I2025), chronic kidney disease (CKD) (ICD-10-CM-N18) and HbA 1c value so as to balance the analysis (1:1 matching) being undertaken

Missing doses or dosing erratically undermines the cumulative effect that drives weight loss, so finding a day you will reliably keep matters more than any single early or late injection

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